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<channel><title><![CDATA[FULLBROOK SYSTEMS - Blog]]></title><link><![CDATA[https://www.fullbrooksystems.co.uk/blog]]></link><description><![CDATA[Blog]]></description><pubDate>Fri, 17 Apr 2026 03:14:57 +0000</pubDate><generator>Weebly</generator><item><title><![CDATA[Optimising Heavy Fuel Oil Stability and Compatibility with the MS 20 MultiScan]]></title><link><![CDATA[https://www.fullbrooksystems.co.uk/blog/optimising-heavy-fuel-oil-stability-and-compatibility-with-the-ms-20-multiscan]]></link><comments><![CDATA[https://www.fullbrooksystems.co.uk/blog/optimising-heavy-fuel-oil-stability-and-compatibility-with-the-ms-20-multiscan#comments]]></comments><pubDate>Thu, 19 Dec 2024 09:54:47 GMT</pubDate><category><![CDATA[Uncategorized]]></category><guid isPermaLink="false">https://www.fullbrooksystems.co.uk/blog/optimising-heavy-fuel-oil-stability-and-compatibility-with-the-ms-20-multiscan</guid><description><![CDATA[When it comes to working with heavy fuel oils, precision in testing and understanding oil stability is critical. One of the biggest challenges faced by the petroleum industry is the destabilisation of asphaltenes.&nbsp;These heavy molecules, present in heavy fuel oils, can lead to significant problems such as heat exchanger fouling;&nbsp;the formation of unwanted, stable oil-water emulsions, and other processing issues. Incompatible heavy oil blends can also cause asphaltene flocculation and dep [...] ]]></description><content:encoded><![CDATA[<div class="paragraph"><span><span style="color:rgb(0, 0, 0)">When it comes to working with heavy fuel oils, precision in testing and understanding oil stability is critical. One of the biggest challenges faced by the petroleum industry is the destabilisation of asphaltenes.&nbsp;</span></span><br /><span><span style="color:rgb(0, 0, 0)">These heavy molecules, present in heavy fuel oils, can lead to significant problems such as heat exchanger fouling;&nbsp;the formation of unwanted, stable oil-water emulsions, and other processing issues. Incompatible heavy oil blends can also cause asphaltene flocculation and deposition, leading to&nbsp;more severe operational disruptions.</span></span><br /><span><span style="color:rgb(0, 0, 0)">Understanding the stability of asphaltenes in heavy fuel oils is essential for preventing these problems&mdash;and the MS 20 MultiScan from </span><a href="https://www.dataphysics.com/"><span style="color:rgb(17, 85, 204); font-weight:400">DataPhysics Instruments</span></a><span style="color:rgb(0, 0, 0)"> is one of the most advanced tools available for this type of analysis.<br /><br /></span></span><u><span><span style="color:rgb(0, 0, 0); font-weight:400"><font size="3">How the MS 20 MultiScan Works for Heavy Fuel Oils</font></span></span></u><br /><span><span style="color:rgb(0, 0, 0)">The MS 20 MultiScan provides a detailed and automated approach to understanding the stability and ageing of liquid dispersions like heavy fuel oils. It uses optical stability analysis to detect changes in the oil, specifically the behaviour of asphaltenes.</span></span><br /><br /><span><span style="color:rgb(0, 0, 0)">Asphaltenes have a unique chemical structure making them insoluble in paraffinic hydrocarbons, like n-heptane, but soluble in aromatic solvents, like toluene. When n-heptane is added to a heavy oil sample, it can cause asphaltene molecules to flocculate. By measuring the transmission of light through the sample, the MS 20 can accurately evaluate the degree and rate of asphaltene flocculation, providing quantitative insight into the oil&rsquo;s stability.</span></span><br /><br /><u><span><span style="color:rgb(0, 0, 0); font-weight:400">Key Features of the MS 20 MultiScan for Heavy Fuel Oil Analysis</span></span></u><br /><span><span style="color:rgb(0, 0, 0)">The MS 20 is equipped with up to six temperature-controlled ScanTowers, allowing each sample chamber to operate at different temperatures ranging from 4&deg;C to 80&deg;C. This flexibility makes it easy to simulate various real-world conditions, such as storage, transport, and processing environments.</span></span><br /><span><span style="color:rgb(0, 0, 0)">Here's how the process works:</span></span><ul><li style="color:rgb(0, 0, 0)"><span><span>A small vial containing the oil sample is placed in one of the MS 20's ScanTowers.</span></span></li><li style="color:rgb(0, 0, 0)"><span><span>The device uses two LEDs of different wavelengths to scan the whole sample height at regular intervals, measuring the backscatter and transmission intensity of light.</span></span></li><li style="color:rgb(0, 0, 0)"><span><span>The transmission intensity data, which indicates the stability of the oil, is then displayed in an intensity-position diagram in MSCsoftware.</span></span></li></ul><br /><span><span style="color:rgb(0, 0, 0)">By observing changes in the transmission intensities, the MS 20, and corresponding MSCsoftware, provides insights into the oil's stability over time, helping you predict how the asphaltenes will behave in various conditions.</span></span><br /><br /><span><span style="color:rgb(0, 0, 0)">The MS 20 MultiScan gives you control over your processes, offering automated precision and flexibility in testing. With features such as ASTM D7061 compliance, customizable temperature control, and real-time data analysis, the MS 20 ensures that you stay ahead of potential problems and maintain the integrity of your heavy oil blends.</span></span><br /><span><span style="color:rgb(0, 0, 0)">If you&rsquo;d like to find out more, </span><a href="https://www.fullbrooksystems.co.uk/contact.html"><span style="color:rgb(17, 85, 204); font-weight:400">please contact us</span></a><span style="color:rgb(0, 0, 0)">. We would welcome the opportunity to tell you about what the Multiscan MS 20 can do and to test some samples for you.&nbsp;</span></span></div>  <div><div class="wsite-image wsite-image-border-medium " style="padding-top:5px;padding-bottom:10px;margin-left:0px;margin-right:10px;text-align:left"> <a href='https://www.fullbrooksystems.co.uk/dataphysics-multiscan-ms20.html' target='_blank'> <img src="https://www.fullbrooksystems.co.uk/uploads/9/3/5/7/93576254/editor/11-12-24-page.png?1734602608" alt="Picture" style="width:auto;max-width:100%" /> </a> <div style="display:block;font-size:90%"></div> </div></div>]]></content:encoded></item><item><title><![CDATA[Are LEDs a suitable alternative to Mercury Lamps in Process photometers ?]]></title><link><![CDATA[https://www.fullbrooksystems.co.uk/blog/are-leds-a-suitable-alternative-to-mercury-lamps-in-process-photometers]]></link><comments><![CDATA[https://www.fullbrooksystems.co.uk/blog/are-leds-a-suitable-alternative-to-mercury-lamps-in-process-photometers#comments]]></comments><pubDate>Fri, 23 Aug 2024 14:35:19 GMT</pubDate><category><![CDATA[Mercury]]></category><guid isPermaLink="false">https://www.fullbrooksystems.co.uk/blog/are-leds-a-suitable-alternative-to-mercury-lamps-in-process-photometers</guid><description><![CDATA[How will the EU decision to ban mercury lamps affect process photometers and the industries that have relied on them for many years?&nbsp;In a significant move towards sustainability and public health, the&nbsp;European Union has decided to ban mercury lamps by 2025. This decision is driven by the need to reduce environmental pollution and protect public health from the toxic effects of mercury.Pharmaceutical companies worldwide have become reliant on mercury lamp based photometry for applicatio [...] ]]></description><content:encoded><![CDATA[<div class="paragraph"><span><font color="#2a2a2a" size="3">How will the EU decision to ban mercury lamps affect process photometers and the industries that have relied on them for many years?&nbsp;</font></span><span style="color:rgb(33, 33, 33)">In a significant move towards sustainability and public health, the&nbsp;</span><a href="https://www.awe.international/article/1860927/plans-total-ban-toxic-mercury-eu-2025#:~:text=European%20Union%20(EU)%20negotiators%20have,%2C%20lamps%2C%20and%20environmental%20safeguards.&amp;text=In%20brief%3A,exceptions%20for%20specific%20medical%20needs."><span style="color:rgb(17, 85, 204); font-weight:400">European Union has decided to ban mercury lamps by 2025</span></a><span style="color:rgb(33, 33, 33)">. This decision is driven by the need to reduce environmental pollution and protect public health from the toxic effects of mercury.</span><br /><br /><span><font color="#2a2a2a" size="3">Pharmaceutical companies worldwide have become reliant on mercury lamp based photometry for applications a varied as&nbsp;</font></span><ul><li><span><font color="#2a2a2a" size="3">Chromatographic&nbsp;&nbsp;</font></span><ul><li><span><span><font color="#2a2a2a" size="3">Separation</font></span></span></li><li><span><span><font color="#2a2a2a" size="3">&#8203;</font></span></span><span><span><font color="#2a2a2a" size="3">Protein measurement</font></span></span></li><li><span><span><font color="#2a2a2a" size="3">Solvent concentration</font></span></span></li><li><span><span><font color="#2a2a2a" size="3">Product detection</font></span></span></li></ul></li><li><span><font color="#2a2a2a" size="3">Trace water content</font></span></li><li><span><font color="#2a2a2a" size="3">Centrifuge control</font></span></li><li><span><font color="#2a2a2a" size="3">Phase separation&nbsp;</font></span></li></ul> <span><font color="#2a2a2a" size="3">And many more&nbsp;</font></span><br /><br /><span><span style="color:rgb(33, 33, 33)"><font size="3">So where does that leave laboratories and facilities that heavily rely on the use of filament lamps, commonly made with mercury, for their production, processes and equipment?&nbsp;&nbsp;</font></span></span><br /><br /><span><span style="color:rgb(33, 33, 33)"><font size="3">LED lamps are the answer. They are widely available and far more eco-friendly. But what are the differences? Here is your guide to Mercury Filament Lamps and LEDs to help you prepare for the regulation change.&nbsp;</font></span></span><br /><br /><strong><span><span style="color:rgb(33, 33, 33)"><font size="3">1. Efficiency</font></span></span></strong><br /><span><span style="color:rgb(33, 33, 33)"><font size="3">Traditional mercury lamps are generally less energy-efficient. They require a significant amount of power to operate and can produce a lot of heat. They also have a warm-up period before they reach full brightness, which can delay the start of analysis. They can also degrade over time, affecting the consistency and accuracy of measurements.</font></span></span><br /><br /><span><span style="color:rgb(33, 33, 33)"><font size="3">LED lamps are much more energy-efficient, consuming less power for the same amount of light output. They reach full brightness instantly and can remain at a consistent level of brightness leading to more accurate readings.&nbsp;</font></span></span><br /><br /><span><span style="color:rgb(33, 33, 33); font-weight:700"><font size="3">2. Longevity</font></span></span><br /><span><span style="color:rgb(33, 33, 33)"><font size="3">The lifespan of mercury lamps is relatively short. They typically need to be replaced more frequently, leading to higher maintenance costs and downtime for the equipment, like analysers, that they may reside in. LEDs have a much longer lifespan, often lasting tens of thousands of hours. Fewer replacements mean less intervention and keeping your laboratories within budget.&nbsp;</font></span></span><br /><br /><span><span style="color:rgb(33, 33, 33); font-weight:700"><font size="3">3. Safety and Environmental Impact</font></span></span><br /><span><span style="color:rgb(33, 33, 33)"><font size="3">Mercury lamps contain mercury, a toxic metal substance that poses environmental and health risks if not handled and disposed of properly. Breakage can release mercury vapour, which is also hazardous. LEDs do not contain mercury or other harmful substances, making them safer for both users and the environment. They are easier to dispose of in the rarer instances where you have to replace them.&nbsp;</font></span></span><br /><br /><span><span style="color:rgb(33, 33, 33); font-weight:700"><font size="3">4. Quality</font></span></span><br /><span><span style="color:rgb(33, 33, 33)"><font size="3">This is the all-important factor.&nbsp; The light spectrum from mercury lamps can be limited and may not be ideal for all types of analysis. They often produce ultraviolet light, which can be useful but also limiting depending on the application. LEDs can be designed to emit specific wavelengths and have a more controlled and customisable light spectrum, making them suitable for a broader range of analytical applications.</font></span></span><br /><span><span style="color:rgb(33, 33, 33)"><font size="3">We understand that many of you will still be using mercury lamps, particularly in the pharmaceutical industry, and changing them can be difficult due to validation costs and constraints. However, with the legislation change on the horizon, we can help you with the transition.&nbsp;</font></span></span><br /><br /><span><font size="3"><span style="color:rgb(33, 33, 33)">Our partners, Kemtrak, have </span><a href="https://www.kemtrak.com/environmental-statement/"><span style="color:rgb(17, 85, 204); font-weight:400">never used mercury in their products</span></a><span style="color:rgb(33, 33, 33)"> and can help your operations go green. Their range of </span><span style="color:rgb(42, 42, 42)">high-performance industrial process photometric, fluorescence and turbidity instruments can be used in a wide variety of applications.&nbsp;&nbsp;</span></font></span><br /><br /><font color="#2a2a2a"><font size="3">Besides the upcoming ban there are good reasons to change from mercury lamp based photometers to LED&rsquo;s as they offer a multitude of benefits.</font></font><ul><li><font color="#2a2a2a" size="3">Long life</font></li><li><font color="#2a2a2a" size="3">Stability</font></li><li><font color="#2a2a2a" size="3">No drift</font></li><li><font color="#2a2a2a" size="3">Cold light</font></li><li><font color="#2a2a2a" size="3">Reliability</font></li><li><font color="#2a2a2a" size="3">Low maintenance</font></li><li><font color="#2a2a2a" size="3">Accurate wavelengths.</font></li></ul><br /><span><font size="3"><span style="color:rgb(42, 42, 42)">The engineering team at here Fullbrook Systems can discuss your specific needs and ease the transition between LED and Mercury lamps. </span><a href="https://www.fullbrooksystems.co.uk/contact.html"><span style="color:rgb(17, 85, 204); font-weight:400">Reach out today.</span></a><span style="color:rgb(42, 42, 42)">&nbsp;</span></font></span><br /><br /></div>]]></content:encoded></item><item><title><![CDATA[Using the Kemtrak DCP007 Photometer for Chromatography Product Detection]]></title><link><![CDATA[https://www.fullbrooksystems.co.uk/blog/using-the-kemtrak-dcp007-photometer-for-chromatography-product-detection]]></link><comments><![CDATA[https://www.fullbrooksystems.co.uk/blog/using-the-kemtrak-dcp007-photometer-for-chromatography-product-detection#comments]]></comments><pubDate>Wed, 17 Aug 2022 00:00:00 GMT</pubDate><category><![CDATA[Chromatography]]></category><guid isPermaLink="false">https://www.fullbrooksystems.co.uk/blog/using-the-kemtrak-dcp007-photometer-for-chromatography-product-detection</guid><description><![CDATA[       The versatility and efficacy of&nbsp;chromatographic techniques&nbsp;have made them essential in both large scale and analytical separation.Chromatography is widely used in bioprocessing to separate protein molecules from concentrated process fluids. The centre of a chromatography system is a column, filled with a media specific to the separation being carried out.How is the Kemtrak DCP007 Photometer used for chromatography product detection?Chromatography is used for protein separation a [...] ]]></description><content:encoded><![CDATA[<div><div class="wsite-image wsite-image-border-none " style="padding-top:10px;padding-bottom:10px;margin-left:0;margin-right:0;text-align:center"> <a> <img src="https://www.fullbrooksystems.co.uk/uploads/9/3/5/7/93576254/dcp007-industrial-photometer-orig_orig.png" alt="Picture" style="width:auto;max-width:100%" /> </a> <div style="display:block;font-size:90%"></div> </div></div>  <div class="paragraph"><span style="color:rgb(63, 63, 63)">The versatility and efficacy of&nbsp;</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206469/" target="_blank">chromatographic techniques</a><span style="color:rgb(63, 63, 63)">&nbsp;have made them essential in both large scale and analytical separation.</span><br /><br /><span style="color:rgb(63, 63, 63)">Chromatography is widely used in bioprocessing to separate protein molecules from concentrated process fluids. The centre of a chromatography system is a column, filled with a media specific to the separation being carried out.</span><br /><br /><strong style="color:rgb(63, 63, 63)"><font size="5">How is the Kemtrak DCP007 Photometer used for chromatography product detection?</font></strong><br /><br /><span style="color:rgb(63, 63, 63)">Chromatography is used for protein separation and purification in biotechnology and can require one or more chromatography steps during downstream processing.</span><br /><br /><span style="color:rgb(63, 63, 63)">Separation through chromatography requires specialized equipment to ensure maximum yield and purity. A&nbsp;</span><a href="https://www.fullbrooksystems.co.uk/inline-photometer-dcp007.html" target="_blank">Kemtrak DCP007-UV photometer</a><span style="color:rgb(63, 63, 63)">&nbsp;is optimally designed for in-line real time measurement and control, allowing the detection of a protein rich solution to be diverted for collection.</span><br /><br /><span style="color:rgb(63, 63, 63)">With an optional NIST Validation accessory mounted it will allow the user to do a validation of instrument in-line in a simple way.</span><br /><br /><strong style="color:rgb(63, 63, 63)"><font size="5">How does the Kemtrak DCP007 Photometer help with measuring protein levels?</font></strong><br /><br /><span style="color:rgb(63, 63, 63)">Advances in&nbsp;</span><a href="https://www.sciencedirect.com/topics/earth-and-planetary-sciences/bioprocessing" target="_blank">bioprocessing methods</a><span style="color:rgb(63, 63, 63)">&nbsp;have led to protein products being expressed and concentrated to higher and higher levels.</span><br /><br /><span style="color:rgb(63, 63, 63)">Higher protein concentrations mean higher absorbance and therefore, UV analysers need the ability to measure accurately at these higher absorbance levels.</span><br /><br /><span style="color:rgb(63, 63, 63)">While absorbance measurement is essentially linear, many traditional instruments use light sources that generate a broad spectrum of wavelengths that cause stray light to enter the measurement cell resulting in a non-linear response to protein concentration, particularly at high levels.</span><br /><br /><span style="color:rgb(63, 63, 63)">Also, traditional light sources are sensitive to temperature, generating a lot of thermal energy, and constantly drift due to deterioration. This makes them unsuitable, particularly for fragile protein molecule work.</span><br /><br /><strong style="color:rgb(63, 63, 63)"><font size="5">How do I install the Kemtrak DCP007 for post-column chromatography monitoring?</font></strong><br /><br /><span style="color:rgb(63, 63, 63)">The&nbsp;</span><a href="https://www.fullbrooksystems.co.uk/inline-photometer-dcp007.html" target="_blank">Kemtrak DCP007-UV analyser</a><span style="color:rgb(63, 63, 63)">&nbsp;will deliver accurate, reliable, and repeatable post column UV and are a minimum requirement during chromatographic separation to ensure good protein fraction purity and maximum yields.</span><br /><br /><span style="color:rgb(63, 63, 63)">With the unique Kemtrak zero dead volume measurement cell installed at the column outlet, the Kemtrak DCP007-UV analyser can provide single or dual wavelength UV absorbance analysis, in real time, for improved control of the separation process.</span><br /><br /><span style="color:rgb(63, 63, 63)">With this, the need for offline testing and manual analyses is greatly reduced. Furthermore, the use of solid-state light sources provides the ability to measure up to 4.5 Au at 280 nm and to monitor high concentration processes up to 90 OD linearly without &ldquo;peak clipping&rdquo; and the undesirable effects of &ldquo;hot&rdquo; and powerful UV light sources on the product.</span><br /><br /><span style="color:rgb(63, 63, 63)">Therefore, the Kemtrak DCP007-UV is the best analyser for chromatographic separation.</span><br /><br /><span style="color:rgb(63, 63, 63)">For more information about how the Kemtrak DCP007 can assist with your chromatography, please contact us at:&nbsp;</span><strong style="color:rgb(63, 63, 63)">sales@fullbrook.com</strong><span style="color:rgb(63, 63, 63)">&nbsp;or call:&nbsp;</span><strong style="color:rgb(63, 63, 63)">01442 876777</strong><span style="color:rgb(63, 63, 63)">.</span></div>]]></content:encoded></item><item><title><![CDATA[Using the Kemtrak DCP007-NIR to improve chromatographic solvent concentration]]></title><link><![CDATA[https://www.fullbrooksystems.co.uk/blog/using-the-kemtrak-dcp007-nir-to-improve-chromatographic-solvent-concentration]]></link><comments><![CDATA[https://www.fullbrooksystems.co.uk/blog/using-the-kemtrak-dcp007-nir-to-improve-chromatographic-solvent-concentration#comments]]></comments><pubDate>Tue, 09 Aug 2022 00:00:00 GMT</pubDate><category><![CDATA[Chromatography]]></category><guid isPermaLink="false">https://www.fullbrooksystems.co.uk/blog/using-the-kemtrak-dcp007-nir-to-improve-chromatographic-solvent-concentration</guid><description><![CDATA[Recently, we looked at how the Kemtrak DCP007-NIR can be used to improve chromatographic separations. In this week&rsquo;s post, we analyse how this popular and diverse instrument can also be used to improve solvent concentration control.The versatility and efficacy of&nbsp;chromatographic techniques&nbsp;have made them essential in both large scale, and analytical separations.Chromatography is widely used in bio-processing to separate protein molecules from concentrated process fluids.The centr [...] ]]></description><content:encoded><![CDATA[<div class="paragraph"><span style="color:rgb(63, 63, 63)">Recently, we looked at how the Kemtrak DCP007-NIR can be used to improve chromatographic separations. In this week&rsquo;s post, we analyse how this popular and diverse instrument can also be used to improve solvent concentration control.</span><br /><br /><span style="color:rgb(63, 63, 63)">The versatility and efficacy of&nbsp;</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206469/" target="_blank">chromatographic techniques</a><span style="color:rgb(63, 63, 63)">&nbsp;have made them essential in both large scale, and analytical separations.</span><br /><br /><span style="color:rgb(63, 63, 63)">Chromatography is widely used in bio-processing to separate protein molecules from concentrated process fluids.</span><br /><br /><span style="color:rgb(63, 63, 63)">The centre of a chromatography system is the&nbsp;</span><a href="https://en.wikipedia.org/wiki/Column_chromatography" target="_blank">column</a><span style="color:rgb(63, 63, 63)">, filled with a media specific to the separation to be carried out.</span><br /><br /><font size="5" style="color:rgb(63, 63, 63)"><strong>How is the technique applied?</strong></font><br /><br /><span style="color:rgb(63, 63, 63)">Solvent gradient control can significantly enhance peak separation and the process economy of chromatography applications.</span><br /><br /><span style="color:rgb(63, 63, 63)">An in-line quantitative sensor permits on-line mobile phase assessment, which with controlled feedback can guarantee accurate and reproducible results.</span><br /><br /><span style="color:rgb(63, 63, 63)">Controlled gradients minimize the effects of changing properties of the stock solvents.</span><br /><br /><font size="5" style="color:rgb(63, 63, 63)"><strong>How was the instrument installed?</strong></font><br /><br /><span style="color:rgb(63, 63, 63)">Pre-Column chromatography monitoring:</span><br /><br /><span style="color:rgb(63, 63, 63)">The&nbsp;</span><a href="https://www.fullbrooksystems.co.uk/inline-photometer-dcp007.html" target="_blank">Kemtrak DCP007-NIR&nbsp;</a><span style="color:rgb(63, 63, 63)">mounted in-line before the chromatography column, continuously monitoring the solvent concentration, gives the user control over the composition delivered to the chromatography column.</span><br /><br /><span style="color:rgb(63, 63, 63)">The online monitoring of solvent composition is more significant than measuring physical parameters like mass flow alone. As It allows the generation of batch reports that confirm the actual gradient composition and inhibits the incorrect use of a solvent.</span><br /><br /><span style="color:rgb(63, 63, 63)">The Kemtrak hygienic measurement cells available with FDA and UPC VI approved materials, convenient zero dead volume design; contain no electronics or moving parts for ease of use.</span><br /><br /><span style="color:rgb(63, 63, 63)">There are two versions of the&nbsp;</span><a href="https://www.fullbrooksystems.co.uk/inline-photometer-dcp007.html" target="_blank">Kemtrak DCP007-NIR</a><span style="color:rgb(63, 63, 63)">&nbsp;currently available:</span><br /><br /><span style="color:rgb(63, 63, 63)">DCP007-NIRL (850 &ndash; 1550 nm) for measurement of 0 - 100% water and solvent gradients.</span><br /><span style="color:rgb(63, 63, 63)">DCP007-NIRH (850 &ndash; 2000 nm) for trace water and hydrocarbon detection. This model incorporates a multiple stage Peltier cooled and temperature regulated photodiodes and NIR LED light source for the very best in stability and performance.</span><br /><br /><span style="color:rgb(63, 63, 63)">For more information about this instrument and how it can help you with your chromatographic processes, please call us on:&nbsp;</span><strong style="color:rgb(63, 63, 63)">01442 87677</strong><span style="color:rgb(63, 63, 63)">&nbsp;or email:&nbsp;</span><strong style="color:rgb(63, 63, 63)">sales@fullbrook.com</strong><span style="color:rgb(63, 63, 63)">, where we will also be happy to provide you with a free, no obligation quote.</span><br />&#8203;</div>]]></content:encoded></item><item><title><![CDATA[The Kemtrak DCP007-NIR Photometer and Chromatographic Separation Improvement]]></title><link><![CDATA[https://www.fullbrooksystems.co.uk/blog/the-kemtrak-dcp007-nir-photometer-and-chromatographic-separation-improvement]]></link><comments><![CDATA[https://www.fullbrooksystems.co.uk/blog/the-kemtrak-dcp007-nir-photometer-and-chromatographic-separation-improvement#comments]]></comments><pubDate>Fri, 01 Jul 2022 00:00:00 GMT</pubDate><category><![CDATA[Chromatography]]></category><category><![CDATA[Photometer]]></category><guid isPermaLink="false">https://www.fullbrooksystems.co.uk/blog/the-kemtrak-dcp007-nir-photometer-and-chromatographic-separation-improvement</guid><description><![CDATA[In this week&rsquo;s blog post, we discuss how&nbsp;Kemtrak&rsquo;s popular photometer&nbsp;can be used to improve the efficiency of chromatographic separation processes.What are chromatographic techniques?Chromatography&nbsp;is widely used in bioprocessing to separate protein molecules from concentrated process fluids. The centre of a chromatography system is a column, filled with a media specific to the separation being carried out.The versatility and efficacy of&nbsp;chromatographic technique [...] ]]></description><content:encoded><![CDATA[<div class="paragraph"><span style="color:rgb(63, 63, 63)">In this week&rsquo;s blog post, we discuss how&nbsp;</span><a href="https://www.fullbrooksystems.co.uk/inline-photometer-dcp007.html" target="_blank">Kemtrak&rsquo;s popular photometer</a><span style="color:rgb(63, 63, 63)">&nbsp;can be used to improve the efficiency of chromatographic separation processes.</span><br /><br /><font size="5" style="color:rgb(63, 63, 63)"><strong>What are chromatographic techniques?</strong></font><br /><br /><a href="https://en.wikipedia.org/wiki/Chromatography" target="_blank">Chromatography</a><span style="color:rgb(63, 63, 63)">&nbsp;is widely used in bioprocessing to separate protein molecules from concentrated process fluids. The centre of a chromatography system is a column, filled with a media specific to the separation being carried out.</span><br /><br /><span style="color:rgb(63, 63, 63)">The versatility and efficacy of&nbsp;</span><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5206469/" target="_blank">chromatographic techniques</a><span style="color:rgb(63, 63, 63)">&nbsp;have made them a crucial part of both large scale and analytical separations.</span><br /><br /><span style="color:rgb(63, 63, 63)">The current methods of chromatographic separation are as follows:</span><br /><br /><a href="https://www.sciencedirect.com/topics/immunology-and-microbiology/gel-filtration" target="_blank"><strong>Gel filtration</strong></a><span style="color:rgb(63, 63, 63)">&nbsp;&ndash; refers to sorting the material by molecular size. The physical dimensions of the molecule determine the separation because proteins are naturally spherical. This means the molecular weight of the protein will be proportional to its size, allowing for separation based on this property. Larger molecules pass more slowly through the column media, while smaller molecules pass through more quickly.</span><br /><br /><a href="https://en.wikipedia.org/wiki/Ion_chromatography" target="_blank"><strong>Ion exchange</strong></a><span style="color:rgb(63, 63, 63)">&nbsp;&ndash; refers to sorting the material by electrical charge. Separation works by opposite charge attraction and like charge repulsion. Using a specific charge within the column media allows for attraction and binding of the molecule(s) of interest.</span><br /><br /><a href="https://www.sciencedirect.com/topics/engineering/hydrophobic-interaction" target="_blank"><strong>Hydrophobic interaction</strong></a><span style="color:rgb(63, 63, 63)">&nbsp;&ndash; refers to sorting the material by degree of Hydrophobicity. Separation relies on polar (hydrophilic) molecules &ldquo;sticking&rdquo; together and repelling those which are non-polar (hydrophobic).</span><br /><br /><a href="https://en.wikipedia.org/wiki/Affinity_chromatography" target="_blank"><strong>Affinity</strong></a><span style="color:rgb(63, 63, 63)">&nbsp;- this method uses a bio-specific binding site. This is a section of a molecule in which the shape and distribution of charged and hydrophobic groups allow for highly specific binding to a corresponding site on another molecule. The fit between the two sites is analogous to a lock and key.</span><br /><br /><strong style="color:rgb(63, 63, 63)"><font size="5">How does chromatography work?</font></strong><br /><br /><span style="color:rgb(63, 63, 63)">Chromatography is a process for separating components of a mixture. To start the process, the mixture is dissolved in a substance called the mobile phase. This then carries it through a second substance called the stationary phase.</span><br /><br /><span style="color:rgb(63, 63, 63)">The different components of the mixture travel through the stationary phase at different speeds, causing them to separate from one another. The nature of the specific mobile and stationary phases determines which substances travel more quickly or slowly, and this is how they are separated. These different travel times are known as retention times.</span><br /><br /><span style="color:rgb(63, 63, 63)">A&nbsp;</span><a href="https://en.wikipedia.org/wiki/Gel_permeation_chromatography" target="_blank">chromatography gel</a><span style="color:rgb(63, 63, 63)">&nbsp;is designed to have one half of this lock and key (the ligand), making it stationary within the column. As the product solution is passed through column, the specific mating molecules are bound in place until they are eluted from the column.</span><br /><br /><span style="color:rgb(63, 63, 63)">Examples of affinity interactions include the binding between antibodies and antigens, and enzymes and substrates.</span><br /><br /><span style="color:rgb(63, 63, 63)">The molecular properties utilised in chromatographic separation can be seen in the figure below:</span><br />&#8203;<br /></div>  <div><div class="wsite-image wsite-image-border-none " style="padding-top:10px;padding-bottom:10px;margin-left:0;margin-right:0;text-align:center"> <a> <img src="https://www.fullbrooksystems.co.uk/uploads/9/3/5/7/93576254/fbs-pic-1-orig_orig.png" alt="Picture" style="width:auto;max-width:100%" /> </a> <div style="display:block;font-size:90%"></div> </div></div>  <div class="paragraph"><span style="color:rgb(63, 63, 63)">Separation through chromatography requires highly specialized equipment to ensure maximum yield and purity. A system may include a variety of instruments and sensors for pre -&nbsp; and post -&nbsp; column control.</span><br /><br /><span style="color:rgb(63, 63, 63)">Nearly all proteins absorb UV light at 280 nm, the primary reason for this is due to the aromatic amino acids, e.g. phenylalanine, tryptophan, tyrosine, and histidine.</span><br /><br /><font size="5" style="color:rgb(63, 63, 63)"><strong>How does installing a Kemtrak DCP007 help improve chromatographic processes?</strong></font><br /><br /><span style="color:rgb(63, 63, 63)">Installing a Kemtrak DCP007-UV photometer, measurement cell at the column outlet, allows the presence of proteins to be detected, and therefore collection/pooling to begin.</span><br /><br /><span style="color:rgb(63, 63, 63)">It is vital that any UV analyser has no dead or hold up volume to ensure crisp, sharp peaks are detected. UV analysers utilizing measurement cells with internal hold up volumes can lower the purity of the collected protein because of dilution. Dilution blurs sharp peak detection lines, and can cause lower yields.</span><br /><br /><span style="color:rgb(63, 63, 63)">Using a&nbsp;</span><a href="https://www.fullbrooksystems.co.uk/inline-photometer-dcp007.html" target="_blank">Kemtrak DCP007-NIR photometer</a><span style="color:rgb(63, 63, 63)">, mounted pre-column to determine solvent concentration/composition, allows for a feedback control of the solvent &ldquo;mobile media&rdquo; feed through the column, and increases the accuracy and repeatability of the chromatography system.</span><br /><br /><span style="color:rgb(63, 63, 63)">With the unique zero dead volume Kemtrak measurement cell installed, the Kemtrak DCP007 analyser can provide single or dual wavelength absorbance analysis, in real time, for improved control of the chromatographic separation processes. Therefore, the Kemtrak DCP007 is the recommended analyser for chromatographic separations.</span><br /><br /><span style="color:rgb(63, 63, 63)">To find out more about the Kemtrak DCP007 (UV or NIR) Photometer, please&nbsp;</span><a href="https://www.fullbrooksystems.co.uk/inline-photometer-dcp007.html" target="_blank">visit our website</a><span style="color:rgb(63, 63, 63)">: or call:&nbsp;</span><strong style="color:rgb(63, 63, 63)">01442 87677</strong><span style="color:rgb(63, 63, 63)">&nbsp;to discuss your requirements further. We will also be happy to provide a free, no obligation quote.</span></div>]]></content:encoded></item><item><title><![CDATA[Kemtrak DCP007 & The ICUMSA Colour Scale]]></title><link><![CDATA[https://www.fullbrooksystems.co.uk/blog/kemtrak-dcp007-the-icumsa-colour-scale]]></link><comments><![CDATA[https://www.fullbrooksystems.co.uk/blog/kemtrak-dcp007-the-icumsa-colour-scale#comments]]></comments><pubDate>Fri, 06 May 2022 00:00:00 GMT</pubDate><category><![CDATA[Photometer]]></category><guid isPermaLink="false">https://www.fullbrooksystems.co.uk/blog/kemtrak-dcp007-the-icumsa-colour-scale</guid><description><![CDATA[The methods, applications, and benefits of the&nbsp;Kemtrak DCP007&nbsp;include the following:&bull;&nbsp;&nbsp; &nbsp;ICUMSA Methods GS 1/3-7, GS 2/3-10 and GS 2/3-10&bull;&nbsp;&nbsp; &nbsp;Determination of the solution colour of white, brown, and raw sugars as well as coloured syrups&bull;&nbsp;&nbsp; &nbsp;Decolourisation of glucose syrups&bull;&nbsp;&nbsp; &nbsp;A charcoal filter alarm&bull;&nbsp;&nbsp; &nbsp;Manufacturing quality and control&bull;&nbsp;&nbsp; &nbsp;Real time in-line contin [...] ]]></description><content:encoded><![CDATA[<div class="paragraph"><span style="color:rgb(63, 63, 63)">The methods, applications, and benefits of the&nbsp;</span><a href="https://www.fullbrooksystems.co.uk/inline-photometer-dcp007.html" target="_blank">Kemtrak DCP007</a><span style="color:rgb(63, 63, 63)">&nbsp;include the following:</span><br /><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;ICUMSA Methods GS 1/3-7, GS 2/3-10 and GS 2/3-10</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;Determination of the solution colour of white, brown, and raw sugars as well as coloured syrups</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;Decolourisation of glucose syrups</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;A charcoal filter alarm</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;Manufacturing quality and control</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;Real time in-line continuous measurement</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;A zero maintenance LED light source that never needs replacing.</span><br /><br /><font size="4" style="color:rgb(63, 63, 63)"><strong>What is the ICUMSA Colour Scale and how is it used in sugar production?</strong></font><br /><br /><span style="color:rgb(63, 63, 63)">The International Commission for Uniform Methods of Sugar Analysis (ICUMSA) describes a range of methods for the colorimetric determination of filtered sugar suspensions at known concentrations (Brix values).</span><br /><br /><span style="color:rgb(63, 63, 63)">The ICUMSA colour scale is used to measure the grade and quality of the sugar. The colour of sugar directly relates to the degree of refining &ndash; raw sugars being dark brown in colour whilst highly refined sugars are white in colour. The ICUMSA colour scale is a measurement of the yellowness of the sugar resulting from residual molasses not removed in the refining process and can be used to monitor and control the manufacturing process.</span><br /><br /><font size="4" style="color:rgb(63, 63, 63)"><strong>How can the Kemtrak DCP007 be applied to this process?</strong></font><br /><br /><span style="color:rgb(63, 63, 63)">The Kemtrak DCP007 process photometer has a high-performance long-life LED light source, precision optical filters and robust fibre optics that results in an ICUMSA colour analyser with outstanding performance and reliability.</span><br /><br /><span style="color:rgb(63, 63, 63)">The Kemtrak DCP007 process photometer is recommended to accurately measure ICUMSA colour. The Kemtrak DCP007 employs proprietary dichromatic measurement technology that compensates for particulates, allowing accurate colour measurement without the need for filtration.</span><br /><br /><span style="color:rgb(63, 63, 63)">Due to the proprietary dichromatic four channel measurement technology, particulates in the process media can be compensated for in real time providing an accurate measure of colour without the need for filtration. A primary &ldquo;absorbing&rdquo; wavelength then accurately measures colour changes in the process medium, while a second reference wavelength, which is not absorbed by the process medium, compensates for particulates and/or fouling of the optical windows.</span><br /><br /><span style="color:rgb(63, 63, 63)">Since optic fibres are used to transfer light to the measurement point and back, the measurement cell contains no electronics, moving parts or sources of heat that result in condensation on the optical surfaces. Standard measurement cells are machined in sanitary grade stainless steel with sapphire windows.</span><br /><br /><font size="4" style="color:rgb(63, 63, 63)"><strong>How should I set up and configure the Kemtrak DCP007 for my own work?</strong></font><br /><br /><span style="color:rgb(63, 63, 63)">ICUMSA recommend the absorption of light at 420nm for white and light-coloured sugars and 560nm for darker sugars. 720nm is recommended for the reference wavelength to measure and compensate for the turbidity of the solution.</span><br /><br /><span style="color:rgb(63, 63, 63)">The Kemtrak DCP007 process photometer will accurately measure ICUMSA colour for a known concentration sample using the Brix value (degrees Brix or &deg;Bx). ICUMSA colour is calculated as follows: ICUMSA Colour = 1000 &times; As/b c</span><br /><span style="color:rgb(63, 63, 63)">Where:</span><br /><span style="color:rgb(63, 63, 63)">As = absorbency of the solution (DCP007 primary measurement)</span><br /><span style="color:rgb(63, 63, 63)">b = the optical path-length (cm)</span><br /><span style="color:rgb(63, 63, 63)">c = concentration (g/mL) (using the Brix value).</span><br /><br /><span style="color:rgb(63, 63, 63)">Colour score is expressed in RBU (reference base units) per ICUMSA standard method(s). Where an end user specific base reference is used, the DCP007 can be adjusted accordingly.</span><br /><br /><span style="color:rgb(63, 63, 63)">The process Brix value, measured using a separate density or refractive index analyser, is input into the Kemtrak analyser through a 4-20mA analogue input to correct for differences in sugar concentration.</span><br /><br /><span style="color:rgb(63, 63, 63)">As an alternative where a live density measurement is not available, process Brix values can be manually entered into the analyser.</span><br /><br /><span style="color:rgb(63, 63, 63)">The Kemtrak DCP007 should be configured for the desired measurement range for maximum resolution and accuracy.</span><br /><br /><span style="color:rgb(63, 63, 63)">An optical path-length of at least 10 cm or more is recommended for low colour white sugars, whilst shorter path-lengths are necessary for darker sugars. Please contact us directly for specific configuration details regarding measurement wavelength and selection of optical path-length for the desired measurement range.</span><br /><br /><font size="4" style="color:rgb(63, 63, 63)"><strong>Where can I find out more about the Kemtrak DCP007?</strong></font><br /><br /><span style="color:rgb(63, 63, 63)">Head over to our dedicated webpage on the&nbsp;</span><a href="https://www.fullbrooksystems.co.uk/inline-photometer-dcp007.html" target="_blank">Kemtrak DCP007</a><span style="color:rgb(63, 63, 63)">&nbsp;for more information on this popular instrument.</span><br /><br /><span style="color:rgb(63, 63, 63)">To discuss your requirements or for a free, no-obligation quote, please call us on:&nbsp;</span><strong style="color:rgb(63, 63, 63)">01442 876777</strong><span style="color:rgb(63, 63, 63)">&nbsp;or email:&nbsp;</span><strong style="color:rgb(63, 63, 63)">sales@fullbrook.com</strong><span style="color:rgb(63, 63, 63)">.</span></div>]]></content:encoded></item><item><title><![CDATA[Kemtrak Petrochemical & Offshore Applications: Crude Oil in Water]]></title><link><![CDATA[https://www.fullbrooksystems.co.uk/blog/kemtrak-petrochemical-offshore-applications-crude-oil-in-water]]></link><comments><![CDATA[https://www.fullbrooksystems.co.uk/blog/kemtrak-petrochemical-offshore-applications-crude-oil-in-water#comments]]></comments><pubDate>Thu, 07 Apr 2022 00:00:00 GMT</pubDate><category><![CDATA[Turbidity]]></category><guid isPermaLink="false">https://www.fullbrooksystems.co.uk/blog/kemtrak-petrochemical-offshore-applications-crude-oil-in-water</guid><description><![CDATA[What is crude oil?&nbsp;Crude oil is a yellow-to-black liquid consisting of hydrocarbons of various molecular weights and other liquid organic compounds.Crude oil will not mix with water, however under certain conditions crude oil will form an oil-in-water emulsion with a turbidity proportional to the oil concentration.The Kemtrak TC007 can be used to measure:&nbsp;&nbsp;&nbsp; 0 &ndash; 10% light crude oil in water&nbsp;&nbsp;&nbsp; Real time continuous measurement&nbsp;&nbsp;&nbsp; Oil in prod [...] ]]></description><content:encoded><![CDATA[<div class="paragraph"><strong style="color:rgb(63, 63, 63)"><font size="4">What is crude oil?</font></strong><br /><span style="color:rgb(63, 63, 63)">&nbsp;</span><br /><span style="color:rgb(63, 63, 63)">Crude oil is a yellow-to-black liquid consisting of hydrocarbons of various molecular weights and other liquid organic compounds.</span><br /><br /><span style="color:rgb(63, 63, 63)">Crude oil will not mix with water, however under certain conditions crude oil will form an oil-in-water emulsion with a turbidity proportional to the oil concentration.</span><br /><br /><span style="color:rgb(63, 63, 63)">The Kemtrak TC007 can be used to measure:</span><br /><br /><ul style="color:rgb(63, 63, 63)"><li>&nbsp;&nbsp;&nbsp; 0 &ndash; 10% light crude oil in water</li><li>&nbsp;&nbsp;&nbsp; Real time continuous measurement</li><li>&nbsp;&nbsp;&nbsp; Oil in produced water</li><li>&nbsp;&nbsp;&nbsp; Condensate and cooling water.</li></ul><br /><strong style="color:rgb(63, 63, 63)"><font size="4">How can the Kemtrak TC007 be used to measure crude oil in water?</font></strong><br /><br /><span style="color:rgb(63, 63, 63)">Crude oil in water can be accurately measured using a Kemtrak TC007 process turbidimeter.</span><br /><br /><span style="color:rgb(63, 63, 63)">One of the main benefits of the Kemtrak TC007 process turbidimeter is that all of the electronics, including the long-life, high performance LED light source and photodetectors, are encased within the TC007 analyser enclosure, allowing safe operation in even the most hazardous of environments.</span><br /><br /><span style="color:rgb(63, 63, 63)">Industrial grade optic fibres are used to transfer low power cold light from within the TC007 analyser enclosure to the sampling point and back.</span><br /><br /><span style="color:rgb(63, 63, 63)">As crude oil will not mix with water, it is vital that the sample under analysis has a turbulent flow to ensure sample homogeneity.</span><br /><br /><span style="color:rgb(63, 63, 63)">The image below shows 5% light crude oil in water directly after being shaken (left) and then after five minutes (right):</span><br />&#8203;</div>  <div><div class="wsite-image wsite-image-border-none " style="padding-top:10px;padding-bottom:10px;margin-left:0;margin-right:0;text-align:center"> <a> <img src="https://www.fullbrooksystems.co.uk/uploads/9/3/5/7/93576254/light-crude-oil-in-water-orig_orig.png" alt="Picture" style="width:auto;max-width:100%" /> </a> <div style="display:block;font-size:90%"></div> </div></div>  <div class="paragraph"><strong style="color:rgb(63, 63, 63)"><font size="4">What were the results of the analysis?</font></strong><br /><br /><span style="color:rgb(63, 63, 63)">The calibration below was made using light crude oil (&rho;=830 kg.m -3 @15&deg;C, &nu;=3.51 mm.s -1 @20 &deg;C) between 0 &ndash; 5 % oil in distilled water.</span><br /><br /><span style="color:rgb(63, 63, 63)">The sample was hand shaken (5s) then immediately analysed.</span><br /></div>  <div><div class="wsite-image wsite-image-border-none " style="padding-top:10px;padding-bottom:10px;margin-left:0;margin-right:0;text-align:center"> <a> <img src="https://www.fullbrooksystems.co.uk/uploads/9/3/5/7/93576254/light-crude-oil-in-water-02-orig_orig.png" alt="Picture" style="width:auto;max-width:100%" /> </a> <div style="display:block;font-size:90%"></div> </div></div>  <div class="paragraph"><font size="4" style="color:rgb(63, 63, 63)"><strong>How do you install the equipment to undertake this analysis of crude oil in water?</strong></font><br /><br /><span style="color:rgb(63, 63, 63)">The most critical factor necessary for this analysis is a turbulent flow. It is recommended to use a narrow bore measurement cell and install this on a bypass line where water is available to zero the instrument and flush the cell when not in use. A narrow bore 1&frasl;4&rdquo; or 1&frasl;2&rdquo; NPT thread type measurement cell is typical for this application.</span><br /><br /><span style="color:rgb(63, 63, 63)">Under operation the high-speed turbulent flow will keep the sapphire windows free from deposits. When not in use the measurement cell should be flushed with water to prevent sticky deposits from accumulating on the optical surfaces.</span><br /><br /><span style="color:rgb(63, 63, 63)">The image below shows the Kemtrak 1&frasl;4&rdquo; NPT industrial fibre optic measurement cell available in 316L, Monel 400, titanium or Hastelloy.</span></div>  <div><div class="wsite-image wsite-image-border-none " style="padding-top:10px;padding-bottom:10px;margin-left:0;margin-right:0;text-align:center"> <a> <img src="https://www.fullbrooksystems.co.uk/uploads/9/3/5/7/93576254/kemtrak-oil-in-water-03-orig_orig.png" alt="Picture" style="width:auto;max-width:100%" /> </a> <div style="display:block;font-size:90%"></div> </div></div>  <div class="paragraph"><span style="color:rgb(63, 63, 63)">The cell has the added benefits of being maintenance free and containing scratch-resistant sapphire windows. In addition, as there are no electronics or moving parts, this makes it the perfect choice for use in hazardous areas.</span><br /><br /><strong style="color:rgb(63, 63, 63)"><font size="4">Where can I find out more about the Kemtrak TC007 and its applications?</font></strong><br /><br /><span style="color:rgb(63, 63, 63)">To discover more about how this popular instrument can help with colour monitoring, chemical concentration, water measurement in organics, and more, please contact us on&nbsp;</span><strong style="color:rgb(63, 63, 63)">01442 876777</strong><span style="color:rgb(63, 63, 63)">&nbsp;or email us at:&nbsp;</span><strong style="color:rgb(63, 63, 63)">sales@fullbrook.com</strong><span style="color:rgb(63, 63, 63)">.</span></div>]]></content:encoded></item><item><title><![CDATA[Inline Refractometers: Applications & Benefits]]></title><link><![CDATA[https://www.fullbrooksystems.co.uk/blog/inline-refractometers-applications-benefits]]></link><comments><![CDATA[https://www.fullbrooksystems.co.uk/blog/inline-refractometers-applications-benefits#comments]]></comments><pubDate>Thu, 20 Jan 2022 00:00:00 GMT</pubDate><category><![CDATA[Inline Measurement]]></category><category><![CDATA[Refractometers]]></category><guid isPermaLink="false">https://www.fullbrooksystems.co.uk/blog/inline-refractometers-applications-benefits</guid><description><![CDATA[Inline process refractometers and sensors can perform industrial measurements continuously, and in real time. This technology is also known as PAT (Process Analytical Technology), and here at Fullbrook Systems, we provide&nbsp;Schmidt &amp; Haensch&rsquo;s&nbsp;leading range of&nbsp;inline refractometers&nbsp;that allow you to monitor and control your processes without product loss or process divergence.With Schmidt &amp; Haensch&rsquo;s process refractometers, quality control and the determinat [...] ]]></description><content:encoded><![CDATA[<div class="paragraph"><span style="color:rgb(63, 63, 63)">Inline process refractometers and sensors can perform industrial measurements continuously, and in real time. This technology is also known as PAT (Process Analytical Technology), and here at Fullbrook Systems, we provide&nbsp;</span><a href="https://schmidt-haensch.com/" target="_blank">Schmidt &amp; Haensch&rsquo;s</a><span style="color:rgb(63, 63, 63)">&nbsp;leading range of&nbsp;</span><a href="https://www.fullbrooksystems.co.uk/inline-refractometers.html" target="_blank">inline refractometers</a><span style="color:rgb(63, 63, 63)">&nbsp;that allow you to monitor and control your processes without product loss or process divergence.</span><br /><br /><span style="color:rgb(63, 63, 63)">With Schmidt &amp; Haensch&rsquo;s process refractometers, quality control and the determination of liquid concentration and mixing ratios becomes simple. Measurements are always reliable and independent of turbidity, colour, absorption, and viscosity. This ensures the highest precision and improved process control.</span><br /><span style="color:rgb(63, 63, 63)">How does Process Analytical Technology work?</span><br /><br /><a href="https://www.sciencedirect.com/topics/chemistry/process-analytical-technology" target="_blank">Process Analytical Technology (PAT)</a><span style="color:rgb(63, 63, 63)">&nbsp;is a manufacturing methodology for high value chemicals and pharmaceuticals. Critical Process Parameters (CPPs) and Key Performance Indicators (KPIs) of the process are comprehended, well-defined and continually monitored to ensure that the pre-defined Critical Quality Attributes (CQA) of the final product are consistently achieved.</span><br /><br /><span style="color:rgb(63, 63, 63)">PAT measures key quality and performance indicators in both raw and in-process materials in real-time. A well-designed PAT-based process is stable, ensuring that the critical parameters and indicators remain within pre-described limits to safeguard product quality and process safety.</span><br /><br /><font size="5" style="color:rgb(63, 63, 63)">What instruments does the range include and what are their benefits?</font><br /><br /><span style="color:rgb(63, 63, 63)">The current range of Schmidt &amp; Haensch inline refractometers include:</span><ul style="color:rgb(63, 63, 63)"><li><a href="https://www.fullbrooksystems.co.uk/inline-refractometer.html" target="_blank">iPR-EX</a>&nbsp;&ndash; this provides permanent inline real-time measurement of the concentration of dissolved solids and is suitable for all applications in explosion-proof areas.</li><li><a href="https://www.fullbrooksystems.co.uk/inline-refractometer.html" target="_blank">SENSO REF Compact Refractometer</a>&nbsp;&ndash; this high precision, compact instrument opens a new field of miniaturization for process refractometers. With a new optical design, the actual sensor is the size of a golf ball.</li><li><a href="https://www.fullbrooksystems.co.uk/inline-refractometer.html" target="_blank">iPR Compact&sup2; Refractometer</a>&nbsp;&ndash; a precise, fast, and reliable refractometer offering permanent, real-time concentration measurement of dissolved solids in solutions or liquids in process.</li><li><a href="https://www.fullbrooksystems.co.uk/inline-refractometer.html" target="_blank">iPR-B&sup3;</a>&nbsp;&ndash; this automatically operating process refractometer measures the refractive index continuously and thus, the concentration of a binary or quasi-binary liquid mixture. The measurement is independent of light intensity from the light emitting diode (LED) and is free from signal drift, providing high precision, and thus better process control. The newly developed process refractometer iPR B&sup3; replaces the well-established iPR Basic&sup2;.</li><li><a href="https://www.fullbrooksystems.co.uk/inline-refractometer.html" target="_blank">iPR-FR&sup2;</a>&nbsp;- this flagship refractometer is outwardly indistinguishable from the iPR-H2, although the integrated optics and electronics are designed to provide a very wide measuring range from 1.3200 &ndash; 1.5300 RI (0-100 Brix). With a resolution of 0.01 Brix, and an accuracy&nbsp; of +/- 0.05 Brix. Due to its integrated water-cooling system, measurements at process temperatures of up to 150 &deg;C are easily achievable.</li><li><a href="https://www.fullbrooksystems.co.uk/inline-refractometer.html" target="_blank">iPR-HR&sup2;</a>&nbsp;- offering the highest resolution and precision, this refractometer can be applied to very low solid concentrations.</li></ul><span style="color:rgb(63, 63, 63)">Look at our inline refractometer comparison chart to quickly compare the differences between each instrument, and see which one will suit you best:</span><br />&#8203;</div>  <div><div class="wsite-image wsite-image-border-none " style="padding-top:10px;padding-bottom:10px;margin-left:0;margin-right:0;text-align:center"> <a> <img src="https://www.fullbrooksystems.co.uk/uploads/9/3/5/7/93576254/inline-refractometer-comparison-chart-orig_orig.png" alt="Picture" style="width:auto;max-width:100%" /> </a> <div style="display:block;font-size:90%"></div> </div></div>  <div class="paragraph"><font size="5" style="color:rgb(63, 63, 63)">Which industries can these refractometers be applied to?</font><br /><br /><span style="color:rgb(63, 63, 63)">The refractometers from Schmidt &amp; Haensch can be used in the following industries:</span><ul style="color:rgb(63, 63, 63)"><li>Food and beverages &ndash; for the quality control of chocolate, coffee, yoghurt, honey, and other food additives, as well as the dilution or evaporation process control in the juice and jam industries.</li><li>Chemical, petrochemical, and chemical fibres &ndash; this includes the concentration measurement of solvents in chemical fibre production, such as sulphuric acid and caustic soda.</li><li>Sugar, starch, and sweeteners &ndash; carry out the Brix measurement of cane sugar, beet sugar, starch and molasses, monitor crystallisation processes or impurity detection in condensate.</li><li>Biofuels &ndash; monitor your bio-extraction and fermentation processes, and measure the concentration of gelatine, glue, citric acid, and lysine.</li><li>Pharmaceuticals &ndash; monitor chemical reactions and use for the quality control of final products in accordance with Pharmacopoeia requirements.</li><li>Pulp and paper &ndash; measure the concentration of modified starch for sizing paper production and monitor the recovery process of black liquor.</li><li>Tobacco &ndash; monitor your washing baths, flavours, and fragrances control, and measure the concentration of active ingredients during extraction.</li><li>Semiconductors and electronics &ndash; monitor the purity of solvents and other chemicals used for etching or cleaning in LCD displays and chip manufacturing.</li><li>Mechanical processing and the mining industry &ndash; measure the concentration of coolants and the dosing of cutting oils and lubricants.</li></ul><br /><span style="color:rgb(63, 63, 63)">To find out more about how our inline refractometers can help you, please call us on:&nbsp;</span><strong style="color:rgb(63, 63, 63)">01442 876777</strong><span style="color:rgb(63, 63, 63)">&nbsp;or email us at:&nbsp;</span><strong style="color:rgb(63, 63, 63)">sales@fullbrook.com</strong><span style="color:rgb(63, 63, 63)">&nbsp;where we will also be happy to provide you with a free, no obligation quote.</span></div>]]></content:encoded></item><item><title><![CDATA[Kemtrak Inline Turbidity Meter]]></title><link><![CDATA[https://www.fullbrooksystems.co.uk/blog/kemtrak-inline-turbidity-meter]]></link><comments><![CDATA[https://www.fullbrooksystems.co.uk/blog/kemtrak-inline-turbidity-meter#comments]]></comments><pubDate>Tue, 02 Nov 2021 00:00:00 GMT</pubDate><category><![CDATA[Inline Measurement]]></category><category><![CDATA[Turbidity]]></category><guid isPermaLink="false">https://www.fullbrooksystems.co.uk/blog/kemtrak-inline-turbidity-meter</guid><description><![CDATA[If your research and production require accurate measurement of light scattering components, both in-line and in real time, then the&nbsp;Kemtrak Inline Turbidity Meter&nbsp;offers an ideal solution.This easy-to-use industrial process fibre optic turbidimeter contains long-life solid state LED lamps and precision fibre optics to provide drift and noise-free measurement at extremely high precision.Hassle free operation is ensured by automatic compensation of sample colour and fouling of the optic [...] ]]></description><content:encoded><![CDATA[<div class="paragraph"><span style="color:rgb(63, 63, 63)">If your research and production require accurate measurement of light scattering components, both in-line and in real time, then the&nbsp;</span><a href="https://www.fullbrooksystems.co.uk/kemtrak-inline-turbidity-mater.html" target="_blank">Kemtrak Inline Turbidity Meter</a><span style="color:rgb(63, 63, 63)">&nbsp;offers an ideal solution.</span><br /><br /><span style="color:rgb(63, 63, 63)">This easy-to-use industrial process fibre optic turbidimeter contains long-life solid state LED lamps and precision fibre optics to provide drift and noise-free measurement at extremely high precision.</span><br /><br /><span style="color:rgb(63, 63, 63)">Hassle free operation is ensured by automatic compensation of sample colour and fouling of the optical windows. The scratch resistant sapphire windows have no electronics or moving parts, making the unit appropriate for use in hazardous areas, as well as making them maintenance free.</span><br /><br /><span style="color:rgb(63, 63, 63)">Other benefits of this popular piece of kit from Kemtrak include:</span><br /><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp; ISO 7027:1999(E) compliant</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp; Reliable and robust infrared LED lamp</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp; Extensive range of robust fibre optic measurement cells</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp; Analogue output (0/4-20 mA)</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp; Local and web based graphical user interface (TCP/IP).</span><br /><br /><strong style="color:rgb(63, 63, 63)">How does the Kemtrak Turbidity Meter work?</strong><br /><br /><span style="color:rgb(63, 63, 63)">The turbidity meter is made up of a control unit, flow cell and fibre optics, and is designed to measure the lack of clarity or &ldquo;cloudiness&rdquo; of a fluid caused by undissolved particles.</span><br /><br /><span style="color:rgb(63, 63, 63)">Modern turbidimeters use a technique called nephelometry, which measures the amount of light scattered at right angles to an incident light beam. Both transmitted light and scattered light at 90&deg; is measured and mathematically combined using a ratio algorithm to calculate the turbidity of the sample.</span><br /><br /><span style="color:rgb(63, 63, 63)">The dual detection system and ratio algorithm then provides a turbidity measurement that has significantly better performance with coloured and/or light absorbing samples.</span><br /><br /><span style="color:rgb(63, 63, 63)">A long-life LED light source is used to produce reliable turbidity measurements from 0.01 to over 4 000 NTU depending upon the configuration of the optical measurement cell or probe. This means the&nbsp;</span><a href="https://www.fullbrooksystems.co.uk/kemtrak-inline-turbidity-mater.html" target="_blank">Kemtrak TC007</a><span style="color:rgb(63, 63, 63)">&nbsp;is an instrument of high accuracy with long-term calibration stability.</span><br /><br /><strong style="color:rgb(63, 63, 63)">What applications is the Kemtrak Turbidity Meter normally used for?</strong><br /><br /><span style="color:rgb(63, 63, 63)">The Kemtrak is typically applied in:</span><br /><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp; Filtration monitoring</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp; Centrifuge control</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp; Interface detection</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp; Phase separation</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp; Leak detection</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp; Oil in water</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp; Quality control</span><br /><br /><span style="color:rgb(63, 63, 63)">To find out more about how this technology can benefit your research, production, or development, get in touch by calling:&nbsp;</span><strong style="color:rgb(63, 63, 63)">01442 876777</strong><span style="color:rgb(63, 63, 63)">, or email us at:&nbsp;</span><strong style="color:rgb(63, 63, 63)">sales@fullbrook.com</strong><span style="color:rgb(63, 63, 63)">.</span><br />&#8203;</div>  <div><div class="wsite-image wsite-image-border-none " style="padding-top:10px;padding-bottom:10px;margin-left:0;margin-right:0;text-align:center"> <a> <img src="https://www.fullbrooksystems.co.uk/uploads/9/3/5/7/93576254/007-with-dn50-triclamp-1-5-orig_orig.jpg" alt="Picture" style="width:auto;max-width:100%" /> </a> <div style="display:block;font-size:90%"></div> </div></div>]]></content:encoded></item><item><title><![CDATA[Kreis Basket Mills]]></title><link><![CDATA[https://www.fullbrooksystems.co.uk/blog/kreis-basket-mills]]></link><comments><![CDATA[https://www.fullbrooksystems.co.uk/blog/kreis-basket-mills#comments]]></comments><pubDate>Tue, 12 Oct 2021 00:00:00 GMT</pubDate><category><![CDATA[Uncategorized]]></category><guid isPermaLink="false">https://www.fullbrooksystems.co.uk/blog/kreis-basket-mills</guid><description><![CDATA[At Fullbrook Systems, we offer a range of&nbsp;Kreis Basket Mills&nbsp;that are designed for milling low-to-medium viscosity products used in the following industries:&bull;&nbsp;&nbsp; &nbsp;Chemical&bull;&nbsp;&nbsp; &nbsp;Pharmaceutical&bull;&nbsp;&nbsp; &nbsp;Cosmetics&bull;&nbsp;&nbsp; &nbsp;Marine, industrial, and leather paints&bull;&nbsp;&nbsp; &nbsp;Printing inks&bull;&nbsp;&nbsp; &nbsp;Protective coatings&bull;&nbsp;&nbsp; &nbsp;Wood varnishes&bull;&nbsp;&nbsp; &nbsp;Ceramic slurry.Kre [...] ]]></description><content:encoded><![CDATA[<div class="paragraph"><span style="color:rgb(63, 63, 63)">At Fullbrook Systems, we offer a range of&nbsp;</span><a href="https://www.fullbrooksystems.co.uk/kreis-basket-mills.html" target="_blank">Kreis Basket Mills</a><span style="color:rgb(63, 63, 63)">&nbsp;that are designed for milling low-to-medium viscosity products used in the following industries:</span><br /><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;Chemical</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;Pharmaceutical</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;Cosmetics</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;Marine, industrial, and leather paints</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;Printing inks</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;Protective coatings</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;Wood varnishes</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;Ceramic slurry.</span><br /><br /><span style="color:rgb(63, 63, 63)">Kreis Basket Mills are fast-running, high-performance batch mills with variable speed adjustment using modern frequency converter technology, ideal for the fine dispersing and grinding in the batch production.</span><br /><br /><span style="color:rgb(63, 63, 63)">When used with the Kreis Dissolver, extremely high product qualities and very short grinding times are achieved. For both processes only one production container is required, and after the pre-dispersion with the Kreis Dissolver the grinding process is carried out in the same container with the Kreis Basket Mill.</span><br /><br /><span style="color:rgb(63, 63, 63)">As well as a laboratory pilot version, the Kreis basket mill can also be purchased with either a flat, vacuum or gas cover. The main features include:</span><br /><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;A cover system for various container diameters&nbsp;&nbsp; &nbsp;</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;Batch sizes of 1 to 5000 litres</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;Fine grinding in batch production (&lt;5 &mu;m)</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;Height-adjustable grinding basket</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp; &nbsp;Cooled grinding basket</span><br /><span style="color:rgb(63, 63, 63)">&bull;&nbsp;&nbsp;&nbsp; Automatic cooling control</span><br /><br /><span style="color:rgb(63, 63, 63)">Key to short production times,&nbsp;</span><a href="https://www.fullbrooksystems.co.uk/kreis-basket-mills.html" target="_blank">Kreis Basket Mills</a><span style="color:rgb(63, 63, 63)">&nbsp;also allow for continuous temperature measurement with limit value and are optimized for operation with KREISIT&reg; grinding beads.</span><br /><br /><span style="color:rgb(63, 63, 63)">Other options include a double pump disc, a mixing container with a double jacket for cooling, a cleaning container, and a drain tray.</span><br /><br /><span style="color:rgb(63, 63, 63)">To find out more about how Kreis Basket Mills can help you with your research, development, and production by contacting us today at:&nbsp;</span><strong style="color:rgb(63, 63, 63)">sales@fullbrook.com</strong><span style="color:rgb(63, 63, 63)">&nbsp;or calling:&nbsp;</span><strong style="color:rgb(63, 63, 63)">01442 876777</strong><span style="color:rgb(63, 63, 63)">.</span></div>  <div><div class="wsite-image wsite-image-border-none " style="padding-top:10px;padding-bottom:10px;margin-left:0;margin-right:0;text-align:center"> <a> <img src="https://www.fullbrooksystems.co.uk/uploads/9/3/5/7/93576254/kreis-basketmill-no-container-orig-orig_orig.jpg" alt="Picture" style="width:auto;max-width:100%" /> </a> <div style="display:block;font-size:90%"></div> </div></div>]]></content:encoded></item></channel></rss>