One of our most popular instruments at Fullbrook Systems is the Turbsican DNS, which offers a unique platform to help you reformulate the future.
This ready-to-use tool is ideal for dispersibility studies, and carries the following benefits:
• No-dilution particle size kinetics – SMLS technology determines particle size in a native state, up to 95% v/v.
• High frequency online measurement – this allows you to measure while mixing directly in the measurement vial or while working in an external reactor.
• A 2 in 1 Turbiscan – determines the stability and dispersibility of your new product with the same instrument and/or in the same experiment.
How can the Turbiscan DNS help with dispersibility and stability studies?
Formulaction’s Turbiscan DNS is a piece of technology at the forefront of direct stability measurement, revealing new opportunities in particle dispersibility studies.
This factor forms the foundation of successful formulation, and is crucial for higher quality dispersions.
To enable this, the Turbiscan DNS is built with the two features of dispersibility and stability, which allows for dispersion characterisation from the first stage of formulation, through to the entire shelf life of the product.
What are dispersibility and stability?
Dispersibility is the ease of dispersing an article into a liquid in terms of the spatial distribution and the particle size.
Studying dispersibility of a new formulation is vital for optimising key parameters such as:
• Therapeutic efficacy
• Film homogeneity
• Sensoral properties.
Monitoring and quantifying dispersibility is also useful for other parameters, including:
• Suspension ability
• Solvent optimisation (e.g. Hansen parameters)
• Digestion studies.
Stability ensures that the initial structure and the end-use properties remain acceptable within the desired time and in the storage or shipping conditions.
By carefully optimising dispersion stability of your products, you can guarantee a long shelf-life and customer satisfaction.
What is Static Multiple Light Scattering (SMLS)?
The Turbiscan DNS uses SMLS to detect particle migration and size variation in liquid dispersions due to the association of two highly sensitive photo detectors placed in transmission (T)[Light which passes straight through the sample]; and Backscattering (BS) [Light that is scattered out of the samples] modes and a moving reading head.
The sample can be scanned while at rest, for stability measurement, or under agitation/on-line for dispersibility studies via the mixing function (T-MIX) and circulation function (T-LOOP).
Due to its ability to work at rest and under agitation, it’s no surprise that this platform is a popular choice for fully characterising new formulations across a range of industries.
What are the other benefits of the Turbiscan DNS?
As well as the above, this instrument also offers:
• Online particle sizing with two options: analysis under agitation or under circulation connected with an external reactor.
• No dilution for certain particle sizes (10nm to 1mm)
• Direct and instant monitoring of processes, from seconds to months.
• Quick and quantified shelf-life testing, with stability measured up to 1,000 times faster than visual control
• Detection and quantification of the whole destabilisation process
• Real stability testing with studies performed under actual storage conditions, with no centrifugation or dilution required.
• A 2-in-1 instrument that allows both dispersibility and stability to be measured during the same experiment set up.
What sectors can the Turbiscan DNS be applied in?
Popular applications of this instrument include:
• Paint & Ink
• Oil & Petroleum
For more information, or for a free, no obligation quote, please email: firstname.lastname@example.org or call: 01442 876777.
October 2016 Fullbrook Systems Ltd move to new premises in Hemel Hempstead. After being in the same offices for many years the company moved to more suitable premises